Quest Gel, 0.4 oz. Oral Syringe

Fort Dodge
Parasiticide-Oral
Dewormer & Boticide

Active Ingredient(s): Contains 20 mg moxidectin/mL (2.0% w/v).

QUESTR is indicated for use in horses and ponies, including breeding mares andstallions, and foals four months of age and older.

Indications: QUESTR (moxidectin) 2% Equine Oral Gel when administered atthe recommended dose level of 0.4 mg moxidectin/kg (2.2 lb) body weight iseffective in the treatment and control of the following stages ofgastrointestinal parasites in horses and ponies:

Large strongyles: Strongylus vulgaris - (adults and L₄/L₅arterial stages); Strongylus edentatus - (adults and tissue stages); Triodontophorusbrevicauda - (adults); Triodontophorus serratus - (adults).

Small strongyles: Cyathostomum spp. - (adults); Cylicocyclus spp.- (adults); Cylicostephanus spp. - (adults); Gyalocephalus capitatus- (adults); Undifferentiated lumenal larvae.

Encysted cyathostomes: Late L₃ and L₄ mucosal cyathostomelarvae.

Ascarids: Parascaris equorum - (adults and L₄ larval stages).

Pin worms: Oxyuris equi - (adults and L₄ larval stages).

Hair worms: Trichostrongylus axei - (adults).

Large-mouth stomach worms: Habronema muscae - (adults).

Horse stomach bots: Gasterophilus intestinalis - (2nd and 3rd instars); Gasterophilusnasalis - (3rd instars).

One administration of the recommended dose rate of QUESTR 2% Equine Oral Gelalso suppresses strongyle egg production through 84 days.

Mode of Action: QUESTR 2% Equine Oral Gel acts by interfering withchloride channel-mediated neurotransmission in the parasite. This results inparalysis and elimination of the parasite. Moxidectin is safe for use in horsesand ponies because it does not have the same injurious effect on the mammaliannervous system.

Dosage and Administration: QUESTR (moxidectin) 2% Equine Oral Gel isspecially formulated as a palatable gel which is easily administered to horsesand ponies.
QUESTR Gel is packaged in ready-to-use Sure-Dial syringes. The syringe iscalibrated in 50-pound increments, up to 1150 pounds. This enables theadministration of the recommended dose level of 0.4 mg moxidectin/kg body weightby choosing a setting consistent with the animal's weight.
How to set the dose: Since the dose is based on the weight of the animal, youneed to use a scale or weight tape to find each animal's weight before treatingwith QUESTR Gel. Once the weight is known, set the dose for each horse or ponyas follows.

1. Hold the syringe with the capped end pointing to the left and so that you cansee the weight measurements and tick marks (small black lines). Each tick markrelates to 50 lbs. of body weight.
2. Turn the green dial ring until the left side of the ring lines up with theweight of the animal.
How to give QUESTR Gel to a horse or pony:
1. Make sure there is no feed in the animal's mouth.
2. Remove the cap from the end of the syringe. Save the cap for reuse.
3. Place the tip of the syringe inside the animal's mouth at the space betweenthe teeth.
4. Gently push the plunger until it stops, depositing the gel on the back of thetongue.
5. Remove the syringe from the animal's mouth and raise the animal's headslightly to make sure it swallows the gel.
6. Replace the syringe cap.

Treating a second horse or pony with the same syringe: If the first animal you treat weighs less than 1150 lbs., there will be gel left in the syringe. You can use this gel to treat other horses or ponies. To set the next dose, add the weight of the animal you want to treat to the dose setting already on thesyringe. For example, if the syringe was first used to treat a 250 lb. animal,the green dial ring is set on 250 lbs. To treat a 500 lb. animal next, move thegreen dial ring to the 750 lb. marking (250+500=750). You need more than onesyringe to treat horses weighing more than 1150 lbs.

Each syringe of QUESTR 2% Equine Oral Gel may be used to treat more than oneanimal especially when dosing foals, ponies and growing and lighter breeds ofhorses. The table below will help estimate the number of horses or ponies thecontents of each syringe will treat.

Precaution(s): Store at or near room temperature 15°C to 30°C (59°F to 86°F). Avoid freezing. If frozen, thaw completely before use. Storepartially-used syringes with the cap tightly secured.

Environmental Safety: Care should be taken to avoid the release of significantvolumes of moxidectin into either ground or free-running water since moxidectinmay be injurious to aquatic life. Sure-Dial syringes and their contentsshould be disposed of in an approved landfill or by incineration.

Caution(s): QUESTR 2% Equine Oral Gel has been formulated specificallyfor use in horses and ponies only. This product should not be used in otheranimal species as severe adverse reactions, including fatalities in dogs, mayresult.

Warning(s): Extreme caution should be used when administering the productto foals, young and miniature horses, as overdosage may result in seriousadverse reactions. Do not use in horses or ponies intended for food.

Human Warning: Do not ingest. If swallowed, induce vomiting. Wash hands andcontaminated skin with soap and water. If accidental contact with eyes occurs,flush repeatedly with water. If irritation or any other symptom attributable toexposure to this product persists, consult your physician. Keep this and alldrugs out of reach of children.

Animal Safety: QUESTR (moxidectin) 2% Equine Oral Gel can be safelyadministered at the recommended dose of 0.4 mg moxidectin/kg body weight tohorses and ponies of all breeds at least 4 months of age or older. Transientdepression, ataxia and recumbency may be seen when very young or debilitatedanimals are treated. In these instances, supportive care may be advisable.Reproductive safety studies demonstrate a wide margin of safety when the productis used in the treatment of estrual and pregnant mares and breeding stallions.

To report adverse drug reactions or to obtain a copy of the Material Safety DataSheet (MSDS) call (800)477-1365.

Discussion: Strategic Protection Programs: Consult your veterinarian forassistance in the diagnosis, treatment, and control of parasitism. For bestcontrol of parasites, all horses and ponies should be included in a strategictreatment program, with particular attention given to high performance animals,brood mares, stallions and foals. In foals, initial treatment is recommended at4 months of age, after which they should be included in a recurrent treatmentprogram. Because QUESTR provides effective control of the mucosal stages ofsmall strongyles (encysted cyathostomes), it is useful in reducing the frequencyof treatment required for successful strategic equine parasite control. Aveterinarian can assist in preparing the best program for your needs.

QUESTR 2% Equine Oral Gel when used at the recommended dose rate suppressesstrongyle egg production through 84 days following a single oral administration.This residual strongyle control reduces pasture contamination and provides aperiod of protection from reinfection for horses and ponies maintained on thesame pasture.

Presentation: QUESTR 2% Equine Oral Gel is available in one syringeapplicator size. Each Sure-Dial syringe contains 0.4 oz (11.3 g) of QUESTR2% Equine Oral Gel which is sufficient to treat a single horse weighing up to1150 lb, or two or more lighter animals with a combined body weight of up to1150 lb.