This is an over the counter product - it does not require prescription.
Panacur® (fenbendazole) Paste 10% contains the active anthelmintic, fenbendazole.
The chemical name of fenbendazole is methyl 5-(phenylthio)-2-benzimidazole carbamate.
gram of Panacur® (fenbendazole) Paste 10% contains 100 mg of fenbendazole and
is flavored with artificial apple-cinnamon liquid.
The antiparasitic action of Panacur® (fenbendazole) Paste 10% is believed to
be due to the inhibition of energy metabolism in the parasite.
Panacur® (fenbendazole) Paste 10% is indicated for the control of large strongyles
(Strongylus edentatus, S. equinus, S. vulgaris), encysted early third
stage (hypobiotic), late third stage and fourth stage cyathostome larvae, small
strongyles, pinworms (Oxyuris equi), ascarids (Parascaris equorum),
and arteritis caused by fourth stage larvae of Strongylus vulgaris in
(fenbendazole) Paste 10% is approved for use concomitantly with an approved
form of trichlorfon. Thichlorfon is approved for the treatment of stomach bots
(Gasterophilus spp.) in horses. Refer to the manufacturer's label for
directions for use and cautions for trichlorfon.
CONTRAINDICATIONS: There are no known contraindications for the use of
Panacur® (fenbendazole) Paste 10% in horses.
Side effects associated with Panacur® (fenbendazole) Paste 10% could not be
established in well-controlled safety studies in horses with single doses as
high as 454 mg/lb (1000 mg/kg) and 15 consecutive daily doses of 22.7 mg/lb
(50 mg/kg). Particularly with higher doses, the lethal action of fenbendazole
may cause the release of antigens by the dying parasites. This phenomenon may
result in either a local or systemic hypersensitive reaction. As with any drug,
these reactions should be treated symptomatically.
(fenbendazole) Paste 10% has been evaluated for safety in pregnant mares during
all stages of gestation with doses as high as 11.4 mg/lb (25 mg/kg) and in stallions
with doses as high as 11.4 mg/lb (25 mg/kg). No adverse effects on reproductivity
were detected. The recommended dose for control of fourth stage larvae of
Strongylus vulgaris, 4.6 mg/lb (10 mg/kg) daily for 5 consecutive days,
has not been evaluated for safety in stallions or pregnant mares.
Parasites: Regular deworming at intervals of six to eight weeks may be
required due to the possibility of reinfection.
Tissue Parasites: In the case of fourth stage larvae of Strongylus
vulgaris, treatment and retreatment should be based on the life cycle and
epidemiology. Treatment should be initiated in the spring and repeated in the
fall after a six-month interval.
Deworming Program for Control of S. vulgaris: Optimum reduction of S.
vulgaris infections is achieved by reducing the infectivity of the pastures.
When horses are running on pastures, in temperate North America, maximum pasture
infectivity occurs in October-December. If horses are removed from those pastures
in January, pasture infectivity will decline to zero by July 1. Egg production
of S. vulgaris is minimal from January through April, peaking in August
and declining to minimal values in December.
Deworming Program:** December 1, February 1, April 1, June 1,
August 1, October 1.
two treatments that are in bold type are the recommended periods when the 5-day
treatment regimen for the control of the migrating larvae of S. vulgaris
should be performed.
For other areas in the world, retreatment periods for the migrating larvae of
S. vulgaris may be different; consult with your veterinarian.
Keep this and all medications out of the reach of children.
using Panacur® (fenbendazole) Paste 10% concomitantly with trichlorfon, refer
to the manufacturer's labels for use and cautions for trichlorfon.
Do not use in horses intended for food.
Panacur® (fenbendazole) Paste 10% is administered orally at a rate of 2.3 mg/lb
(5 mg/kg) for the control of large strongyles, small strongyles, and pinworms.
One syringe will deworm a 2,500 lb horse. For foals and weanlings (less than
18 months of age) where ascarids are a common problem, the recommended dose
is 4.6 mg/lb (10 mg/kg); one syringe will deworm a 1250 lb horse. For control
of encysted early third stage (hypobiotic), late third stage and fourth stage
cyathostome larvae, and fourth stage larvae of Strongylus vulgaris, the
recommended dose is 4.6 mg/lb (10 mg/kg) for 5 consecutive days; administer
one syringe for each 1250 lbs of body weight per day.
PRECAUTIONS FOR RETREATMENT RECOMMENDATIONS.
Determine the weight of the horse.
Remove syringe tip.
Turn the dial ring until the edge of the ring nearest the tip lines up with
Depress plunger to advance paste to tip.
Now set the dial ring at the graduation nearest the weight of the horse (do
Horse's mouth must be free of food.
Insert nozzle of syringe through the interdental space and deposit the paste
on the back of the tongue by depressing the plunger.
at or below 25°C (75°F)
YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT AND CONTROL OF