This is an over the counter product - it does not require prescription.
Diphenhydramine is an antihistamine used in the treatment of allergies, insect
bites or stings and other causes of itching. It is also used for its sedative
and antiemetic effects in the treatment of motion sickness and travel anxiety.
It is also used for its antitussive effect.
Diphenhydramine is a non-prescription (OTC) product available as 25mg and 50mg
tablets or capsules as well.
How this medicine should be used:
Diphenhydramine is FDA approved for external use in dogs and cats. Diphenhydramine
oral and injectable is not FDA approved for use in veterinary medicine; however,
it is a commonly accepted practice to use this medication in dogs and cats.
The usual dose in dogs and cats is 0.5-2mg/pound every 8-12 hours. The slow
release capsule should not be mixed or dissolved in food. Do not use diphenhydramine
found in combination products containing sinus or cold medicine.
What are the side effects:
Side effects of diphenhydramine include drowsiness, dry mouth and urinary retention.
Rarely, vomiting and diarrhea can occur.
What special precautions are there:
Do not use this medication in animals that are allergic to it or other antihistamines.
Do not use in animals with glaucoma, prostate disease, urinary obstruction,
and high blood pressure. Do not use in pregnant or nursing animals. Use with
caution when given with other CNS depressant drugs such as tranquilizers or
barbiturates. Always tell your veterinarian and pharmacist what other medications
your pet is taking.
In the event of an overdose:
Contact your veterinarian or veterinary emergency room. Symptoms of overdose
can include seizures, extreme drowsiness, coma, respiratory depression and death.
How should I store this medication:
Keep this medication in the container it came in, tightly closed. Store this
medication at room temperature, away from excess heat, light and moisture. Do
not store in the bathroom. Throw away any medication that is outdated or no
Keep medication away from children and pets.
This information sheet is for educational purposes only and is intended to be
a supplement to, and not a substitute for, the expertise and professional judgment
of your veterinarian. The information is NOT to be used for diagnosis or treatment
of your pet. You should always consult your own veterinarian for specific advice
concerning the treatment of your pet.
The information is not intended to cover all possible uses, directions, precautions,
warnings, allergic reactions, drug interactions or adverse effects, nor should
it be construed to indicate that use of a particular drug is safe, appropriate
or effective for your pet. It is not a substitute for a veterinary exam, and
it does not replace the need for services provided by your veterinarian.
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