The performance and mobility of your horse is dramatically affected by how well his joints function. While physical conditioning can strengthen muscles, bones, and tendons, the tremendous forces exerted on the skeletal joints (fetlock, knee, stifle and hock) during training and competition causes wear and tear to the joint cartilage. Since Cosequin provides nutrients that affect the structure and function of the joint, changes may occur gradually. You should notice changes in three to four weeks in most candidates. Some horses may take five to six weeks to exhibit noticeable change